Scientist I

Position: Scientist I

Dept: gRED Gene Therapy

Reporting to: Scientist IV, Analytical

Location: San Diego, CA (Poseida)

Fully Onsite Role

Position Summary:

• is searching for an outstanding Scientist I to join the Gene Therapy team in San Diego, CA. This position offers an exciting opportunity to work with new non-viral nucleic acid delivery tools for in vivo and ex vivo genome editing and gene therapy applications. This person will be engaged in the analysis of Client nanoparticle-based pharmaceuticals.

Responsibilities (may include but are not limited to):

Work at the direction of Analytical scientists to quantitate lipid nanoparticles (LNPs) encapsulating nucleic acids

Analyze raw materials for LNP formulations

Establish relationships between physiochemical characteristics of experimental nanoparticle formulations and their efficacy and safety

Maintain detailed records of analytical data

Interface directly with other functional teams

Share responsibility for basic lab management activities (supply ordering, instrument calibration, maintaining schedules)

Requirements, Knowledge, Skills, and Abilities:

Education \& Experience

Master’s or Bachelor’s degree with 0-2 years’ experience or Master’s or Bachelor’s degree with 2\+ years’ experience in pharmaceutical sciences, bioengineering, chemical engineering, chemistry, or a related scientific discipline. (An equivalent combination of education and experience may be considered.)

Technical Skills

Proficiency at formulating buffers is required.

Practical experience using analytical methods such as RiboGreen, Dynamic Light Scattering (DLS), and Zeta potential measurement is strongly preferred.

Prior Experience With High-Performance Liquid Chromatography (HPLC) Is Preferred.

Experience and proficiency with other analytical techniques will be considered.

Proficiency at MS Excel is required; prior experience with advanced analytical software (Prism, JMP) is desirable.

Core Competencies

Excellent attention to detail and ability to produce consistent results and effectively communicate them to the team

Ability to be a team player, multitask, work on multiple projects at once, and excel in a collaborative work environment

Excellent oral and written communication skills