Director of Engineering, AI Products

Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.

The Team

CZI supports the science and technology that will make it possible to help scientists cure, prevent, or manage all diseases by the end of this century. While this may seem like an audacious goal, in the last 100 years, biomedical science has made tremendous strides in understanding biological systems, advancing human health, and treating disease.

Achieving Our Mission Will Only Be Possible If Scientists Are Able To Better Understand Human Biology. To That End, We Have Identified Four Grand Challenges That Will Unlock The Mysteries Of The Cell And How Cells Interact Within Systems — Paving The Way For New Discoveries That Will Change Medicine In The Decades That Follow

• Building an AI-based virtual cell model to predict and understand cellular behavior
• Developing state-of-the-art imaging systems to observe living cells in action
• Instrumenting tissues to better understand inflammation, a key driver of many diseases
• Engineering and harnessing the immune system for early detection, prevention, and treatment of disease

CZI’s work in science includes grant making programs, open-source software development, and close collaboration with the Chan Zuckerberg Biohub Network. The CZ Biohub Network includes the San Francisco, Chicago, and New York Biohubs as well as the Chan Zuckerberg Imaging Institute. CZI also collaborates with institutional partners like the Kempner Institute for the Study of Natural \& Artificial Intelligence at Harvard University. Join us in accelerating science.

The AI Products team builds software products that transform AI models and biological data into scalable applications that accelerate scientific discovery. Working closely with AI model developers, researchers, and biologists, we connect the dots between research and scientific impact.

The Opportunity

As Director of Engineering for the AI Products group, you will lead a world-class team of passionate engineers building transformative tools at the intersection of AI and biology. Your work will power the next generation of products that accelerate the analysis and interpretation of complex biological data using cutting-edge foundation models.

You’ll tackle ambitious technical challenges — from scaling model inference to production-grade performance, to designing intuitive systems for exploring multi-dimensional, high-resolution cellular imagery and video. You’ll also help architect platforms capable of processing and visualizing protein datasets at unprecedented scale, spanning more than a billion proteins.

This is an opportunity to shape the future of AI-driven biology while leading a team that turns breakthrough research into impactful, real-world solutions.

What You'll Do

• Lead an engineering team focused on building reliable, scalable, extensible software products.
• Work cross-functionally with internal and external partners to develop and deliver on the roadmap, and to shape the long-term strategy for how AI Products drive our scientific impact ambitions.
• Participate in and encourage Agile software development practices to deliver frequent value to our users and enable continuous feedback loops.
• Set the technical direction, guide the team’s technical decisions, and ensure that best practices are consistently followed.
• Ensure high quality in the work we deliver and serve as a hands-on manager to the team.
• Provide mentorship and career development support to direct reports.
• Hire and onboard engineers to fill resource gaps while building out a diverse team.

What You'll Bring

• 12\+ years of experience in Software Engineering, including 5\+ years of engineering leadership as a people manager.
• Proven track record of architecting, delivering, and operating petabyte-scale data platforms across hybrid on-premises and cloud environments, enabling model training on rapidly evolving data modalities.
• Deep technical expertise with the ability to translate complex theory into practical, scalable solutions—driving research, rigorous analysis, clear conclusions, and decisive execution.
• Extensive experience hiring, managing, and developing high-performing engineering teams while cultivating a culture of excellence, ownership, and impact.
• Strong cross-functional collaborator, partnering with interdisciplinary stakeholders to define product strategy, shape requirements, and deliver robust software solutions.
• Influential and empathetic leader who provides clear, direct guidance, inspires collaboration, and consistently coaches engineers to accelerate their technical growth and career progression.
• Active contributor to architectural strategy and technical design decisions, elevating engineering standards and long-term system quality.

Compensation

The Redwood City, CA base pay range for a new hire in this role is $323,000 - $444,400\. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

Better Together

As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.

Benefits For The Whole You

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.

• Provides a generous employer match on employee 401(k) contributions to support planning for the future.
• Paid time off to volunteer at an organization of your choice.
• Funding for select family-forming benefits.
• Relocation support for employees who need assistance moving

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.