Senior Scientist (Cell Line Development)

Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. We have an opening for a Senior Scientist (Cell Line Development) to work on-site in support of projects focused on vaccines and biologics at the National Institutes of Health in Gaithersburg, MD.

This is a long-term contract position which offers:

• Competitive compensation and comprehensive benefit package

• Optional health, vision, and dental plans

• Paid leave as well as 11 paid federal holidays and 401K plan.

• Access to NIH’s unparalleled resources and niche scientific initiatives

KEY TASKS

(1) Plan and execute the generation of stable cell lines for preclinical and clinical material production to advance candidates including monoclonal antibodies, recombinant proteins, and virus like particles.

(2) Perform gene synthesis including oligo synthesis, plasmid design, and construction.

(3) Use molecular biology techniques, including RT-PCR and NGS, for genetic characterization of cell lines.

(4) Execute all steps of the process including plasmid construction, stable pool generation, single cell cloning, and top clone selection

(5) Draft and verify data for CMC sections of pre-IND and IND documents to ensure successful registration of candidates

(6) Prepare manuscripts, technical reports, SOPs, data presentations, and documents needed for meetings, technology transfer and regulatory filings

REQUIREMENTS

(1) Master’s or Ph.D. degree in Immunology, Molecular Biology, Biochemistry, Bioengineering, or a related field

(2) Minimum of 2 years of experience in an industrial setting focused on the development of and engineering stable cell lines for vaccine and biotherapeutic candidates

(3) Extensive hands-on experience with aseptic technique and mammalian cell culture to generate and screen clonally derived cell lines to produce monoclonal antibodies or vaccine candidates

(4) Expertise designing and constructing plasmids for gene expression using molecular cloning methods

(5) Experience using technologies for cell line engineering and molecular biology techniques for genetic characterization of cell lines