Research Associate - Upstream

Research Associate, Process Development Upstream

Location:

Tustin, CA

About the Role

We are partnering with a leading clinical and commercial biologics CDMO focused on developing and manufacturing life-saving biopharmaceuticals. They are seeking a Research Associate to support the development, optimization, and scale-up of mammalian cell culture processes used in biologics production. This role offers the opportunity to work on cutting-edge bioprocess development projects, helping bring innovative therapies from development into manufacturing.

Key Responsibilities

• Develop and optimize mammalian cell culture processes for recombinant protein production.
• Maintain and culture mammalian cell lines including CHO, HEK, NSO, and related expression systems.
• Perform media optimization, feed screening, and process improvement studies to enhance cell growth and productivity.
• Operate, monitor, troubleshoot, and maintain shake flasks, wave bioreactors, and stirred-tank bioreactors.
• Prepare cell culture media and feed formulations from scratch using aseptic techniques.
• Analyze growth, productivity, and nutrient consumption data using Excel and other analytical tools.
• Create technical reports, data summaries, presentations, and process documentation to support project and regulatory requirements.
• Collaborate with cross-functional teams to scale up and transfer processes into manufacturing operations.
• Research and implement new technologies and methodologies to improve upstream development activities.

Qualifications \& Requirements

• B.S. degree in Biological Sciences, Biotechnology, Biochemistry, Molecular Biology, or a related scientific discipline.
• 2\+ years of industry experience in mammalian cell culture, upstream process development, or bioprocessing.
• Hands-on experience with mammalian cell lines and aseptic cell culture techniques.

This position is not eligible for visa sponsorship or support such as H1B, TN, E-3, CPT, OPT, STEM OPT, or employment-based permanent residence processes, now or in the future.