Scientist, Functional Genomics

Our

Functional Genomics

program studies what roles variants classified as "of unknown significance", "possibly damaging" and "likely deleterious" play in human health and disease. Your job will include taking deep dives on suspected pathogenic SNPs and other variants to determine if they are indeed deleterious to protein/cellular/systems-level function, taking the SNP from gene(s) to phenotype.

With ICR, you'll get to:

• Research the potential functional impact of any given SNP on protein or cellular function: from RNA to protein to cell to systems-level analysis including work on known disease-associated SNPs and VUSs in the context of various human primary and iPSC-derived cell types
• Project manage out-sourced work with CROs to maximize your productivity
• Collaborate with other ICR scientists and groups, including Translational Bioinformatics and Genomics, to solve complex human medical mysteries
• Identify potentially actionable targets for therapeutic development

Please apply if you have:

• PhD in Biomedical Sciences
• In-depth knowledge of and experience with modern molecular and cellular biology techniques
• Experience creating and validating stem cell-derived disease models
• Programming experience (R and Python)
• Even if you don't meet all of these criteria, please apply anyway

And you'll need:

• The ability to work in the United States without sponsorship
• To have an easygoing, hard-working personality

Position title and compensation are commensurate with experience.

**The compensation ranges listed below are

starting

ranges.**

**Starting

base salary range: $125,000/yr - $175,000/yr**

**Starting

bonus range: $7,500/yr - $17,500/yr**