Senior Clinical Research Associate

We are partnering with a large CRO to find an experienced Senior Clinical Research Associate based in the United States for a permanent, full-time position. This is a genuine career opportunity for a seasoned CRA looking to grow long-term within a stable, established organization, rather than a short-term contract.

The Role

You'll manage a portfolio of sites local to your home region, balancing remote monitoring with regular in-person visits (approximately 8 to 10 days onsite per month). Site assignments will be localised to where you are based, so travel stays manageable and sustainable. As a permanent member of the team, you'll take ownership of the full monitoring lifecycle, from site qualification through to close-out, while acting as a trusted point of contact for investigators and site staff, with real opportunity for progression as the CRO's project portfolio grows.

Key Responsibilities

• Conduct qualification, initiation, interim monitoring, and close-out visits across assigned sites in your local region
• Perform source document verification, CRF review, and query resolution across paper and EDC systems
• Ensure ongoing site compliance with ICH-GCP, FDA regulations (21 CFR Parts 50, 56, and 312), and applicable state-level requirements
• Identify site-level risks proactively and work with sites to resolve issues before they escalate
• Review subject safety data and informed consent documentation
• Maintain accurate, timely documentation and TMF filings
• Oversee IP accountability, storage, and reconciliation at site level
• Build and maintain strong relationships with investigators, site teams, sponsors, and internal stakeholders
• Provide mentoring and guidance to junior CRAs as part of a growing internal team
• Balance a mixed remote/onsite model efficiently, managing your own schedule and local travel

About You

• Based in the United States, with sites assigned local to your home region, but occasional further travel
• 5\+ years' CRA experience, with a strong monitoring track record across multiple sites
• Solid grounding in ICH-GCP and FDA regulatory requirements, including familiarity with IND-related monitoring and IRB processes
• Confident working independently, with strong self-organisation and time management
• Comfortable with a hybrid remote/onsite rhythm and regular local travel
• Experience with CTMS and EDC platforms
• Excellent written and verbal communication skills
• Life sciences, nursing, or related degree/qualification
• Looking for long-term stability and progression within a growing CRO, rather than a short-term or project-based engagement